When an archaeologist is murdered in his Cairo apartment, an ancient artifact is stolen from his safe - one believed to hold the clue to the Last Secret Chamber. When Joey Peruggia discovers that the dead man was his long-lost uncle, he travels with his girlfriend, Marie, and his friend Boyce, who works for the French intelligence, to Egypt, on a mission to find answers. But once they arrive, they are lured into a trap and become hostages to a crazed man and his gang of thieves; this is a man who will stop at nothing to discover what lies in the last secret chamber.