In one ancient variation on the myth of Pandora's Box, there were two jars, one for Pandora and one for her sister, Anesidora. One contained all the blessings of the gods, the other all the world's curses. Now, in a subterranean city in Northern Iraq, archaeologist Sophie Durand has discovered a secret chamber covered in writing that confirms that version of the tale--a chamber which contains a single jar. "Weird shit" expert Ben Walker joins Sophie's team just as the mystery deepens and grows ugly. Those who believe the myth want to know which jar has been found in the Pandora Room, the one containing blessings, or the one full of curses. Governments rush to lay claim, but jihadi forces aren't waiting for the dust to settle. Whatever the jar contains, they want it, no matter who they have to kill...or what will emerge when they open it. For Sophie, Walker, and the others, the Pandora Room may soon become their tomb.