Special Agent John Harmon is called back into action when the CIA stumbles upon evidence that a dangerous group of extremists is planning to join forces with a drug cartel. He assembles a high-tech team of operatives and devises a daring operation to turn the two groups against each other in an explosive confrontation.

Alexander Coates' criminal empire has been good to him and devastating to his enemies until his number one hit-man, Roman Hurst, messes up what should have been a routine hit. Alexander spares his protégé's life, but cripples his hands, thus 'retiring' Hurst forever. Before long, Alexander realizes that he'll need Hurst's help with assistance from Jimmy Peanuts one last time when Iceman, a ruthless killer, surfaces.